Epsin 1 antibody (AA 140-220)

Catalog No. ABIN7214786

The Rabbit Polyclonal anti-Epsin 1 antibody is suitable to detect Epsin 1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Epsin 1 antibody (AA 140-220) (ABIN7214786)

Target: Epsin 1 (EPN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epsin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Epsin 1 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-Epsin 1 Polyclonal Antibody

Specificity: Epsin 1 Polyclonal Antibody detects endogenous levels of Epsin 1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Epsin 1 at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Epsin 1

Target: Epsin 1 (EPN1)

Alternative Name: Epsin 1

Background: EPN1, Epsin-1, EH domain-binding mitotic phosphoprotein, EPS-15-interacting protein 1EPN1 encodes a member of the epsin protein family. The encoded protein (epsin 1) binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of EPN1 is associated with reduced tumor growth and progression in certain cancer types.

Molecular Weight: 85kD

Gene ID: 29924

UniProt: Q9Y6I3

Pathways: EGFR Signaling Pathway, EGFR Downregulation