ERAS antibody (AA 160-240)

Catalog No. ABIN7221562

This Rabbit Polyclonal antibody specifically detects ERAS in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ERAS antibody (AA 160-240) (ABIN7221562)

Target: ERAS (ES cell expressed Ras (ERAS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ERAS Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-E-Ras Polyclonal Antibody

Specificity: E-Ras Polyclonal Antibody detects endogenous levels of E-Ras protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human E-Ras at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ERAS

Target: ERAS (ES cell expressed Ras (ERAS))

Alternative Name: E-Ras

Background: ERAS, HRAS2, HRASP, GTPase ERas, E-Ras, Embryonic stem cell-expressed RasERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.

Molecular Weight: 25kD

Gene ID: 3266

UniProt: Q7Z444