EXTL3 antibody

Catalog No. ABIN7228454

This Rabbit Polyclonal antibody specifically detects EXTL3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for EXTL3 antibody (ABIN7228454)

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EXTL3 Antibody

Purpose: Rabbit Anti-EXTL3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of EXTL3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human EXTL3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3

Background: Exostosin-like 3, EXT-related protein 1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3EXTL3 gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants.

Molecular Weight: 101kD

Gene ID: 2137

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling