ESYT1 antibody

Catalog No. ABIN7228448

This Rabbit Polyclonal antibody specifically detects ESYT1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ESYT1 antibody (ABIN7228448)

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESYT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ESYT1 Antibody

Purpose: Rabbit Anti-ESYT1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ESYT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ESYT1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ESYT1

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Alternative Name: ESYT1

Background: Extended synaptotagmin-1, E-Syt1, Membrane-bound C2 domain-containing proteinBinds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.

Molecular Weight: 121kD

Gene ID: 23344

UniProt: Q9BSJ8