FANCG antibody (pSer383)

Catalog No. ABIN7220438

This Rabbit Polyclonal antibody specifically detects FANCG in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for FANCG antibody (pSer383) (ABIN7220438)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FANCG Antibody

Binding Specificity: pSer383

Purpose: FANCG (phospho Ser383) Polyclonal Antibody

Specificity: Phospho-FANCG (S383) Polyclonal Antibody detects endogenous levels of FANCG protein only when phosphorylated at S383.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human FANCG Phospho-Ser383

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background: Rabbit Anti-FANCG (phospho Ser383) Polyclonal Antibody,FANCG, XRCC9, Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9,The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. FANCG encodes the protein for complementation group G.,Fanconi anemia group G protein

Molecular Weight: observerd band 69kDa

Gene ID: 2189

UniProt: O15287

Pathways: DNA Damage Repair