FAF1 antibody (Internal Region)

Catalog No. ABIN7217848

The Rabbit Polyclonal anti-FAF1 antibody is suitable to detect FAF1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for FAF1 antibody (Internal Region) (ABIN7217848)

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FAF1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-FAF1 Polyclonal Antibody

Specificity: FAF1 Polyclonal Antibody detects endogenous levels of FAF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human FAF1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1

Background: FAF1, UBXD12, UBXN3A, CGI-03, FAS-associated factor 1, hFAF1, UBX domain-containing protein 12, UBX domain-containing protein 3AInteraction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. FAS-associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.

Molecular Weight: 75kD

Gene ID: 11124

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location