FAF1 antibody (AA 500-580)

Catalog No. ABIN7219244

The Rabbit Polyclonal anti-FAF1 antibody (ABIN7219244) specifically detects FAF1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FAF1 antibody (AA 500-580) (ABIN7219244)

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FAF1 Antibody

Binding Specificity: AA 500-580

Purpose: Rabbit Anti-FAF1 Polyclonal Antibody

Specificity: FAF1 Polyclonal Antibody detects endogenous levels of FAF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human FAF1 at AA range: 500-580

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1

Background: FAF1, UBXD12, UBXN3A, CGI-03, FAS-associated factor 1, hFAF1, UBX domain-containing protein 12, UBX domain-containing protein 3AInteraction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The Fas associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by FAF1 requires a ubiquitin-like domain but not the FAS-binding domain.

Molecular Weight: 75kD

Gene ID: 11124

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location