TNNC2 antibody

Catalog No. ABIN7231856

The Rabbit Polyclonal anti-TNNC2 antibody is suitable to detect TNNC2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for TNNC2 antibody (ABIN7231856)

Target: TNNC2 (Fast Skeletal Troponin C (TNNC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TNNC2 Antibody

Purpose: Rabbit Anti-TNNC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TNNC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TNNC2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TNNC2

Target: TNNC2 (Fast Skeletal Troponin C (TNNC2))

Alternative Name: TNNC2

Background: Troponin C, skeletal muscleTNNC2 (Troponin C2, Fast Skeletal Type) is a Protein Coding gene. Diseases associated with TNNC2 include Distal Arthrogryposis. Among its related pathways are Calcium signaling pathway and Striated Muscle Contraction. Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by TNNC2 is the Tn-C subunit.

Molecular Weight: 17kD

Gene ID: 7125

UniProt: P02585