FAT Atypical Cadherin 2 (FAT2) antibody

Catalog No. ABIN7228490

The Rabbit Polyclonal anti-FAT Atypical Cadherin 2 antibody is suitable to detect FAT Atypical Cadherin 2 in samples from Human, Mouse and Rat. It has been validated for IF and IHC.

Quick Overview for FAT Atypical Cadherin 2 (FAT2) antibody (ABIN7228490)

Target: FAT Atypical Cadherin 2 (FAT2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details

Purpose: Rabbit Anti-FAT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FAT2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FAT2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: FAT Atypical Cadherin 2 (FAT2)

Alternative Name: FAT2

Background: Protocadherin Fat 2, hFat2, Cadherin family member 8, Multiple epidermal growth factor-like domains protein 1, Multiple EGF-like domains protein 1FAT2 gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.

Molecular Weight: 478kD

Gene ID: 2196

UniProt: Q9NYQ8