FA2H antibody (AA 101-150)

Catalog No. ABIN7228460

The Rabbit Polyclonal anti-FA2H antibody is suitable to detect FA2H in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for FA2H antibody (AA 101-150) (ABIN7228460)

Target: FA2H (Fatty Acid 2-Hydroxylase (FA2H))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FA2H antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FA2H Antibody

Binding Specificity: AA 101-150

Purpose: Rabbit Anti-FA2H Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FA2H

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FA2H protein at AA range: 101-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FA2H

Target: FA2H (Fatty Acid 2-Hydroxylase (FA2H))

Alternative Name: FA2H

Background: Fatty acid 2-hydroxylase, Fatty acid alpha-hydroxylaseFA2H encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in FA2H have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

Molecular Weight: 55kD

Gene ID: 79152

UniProt: Q7L5A8