FOSB antibody

Catalog No. ABIN7214928

The Rabbit Polyclonal anti-FOSB antibody is suitable to detect FOSB in samples from Human, Mouse and Monkey. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for FOSB antibody (ABIN7214928)

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FOSB Antibody

Purpose: Rabbit Anti-Fos B Polyclonal Antibody

Specificity: Fos B Polyclonal Antibody detects endogenous levels of Fos B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Fos B around the non-phosphorylation site of S27

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: Fos B

Background: FOSB, G0S3, Protein fosB, G0/G1 switch regulatory protein 3The Fos gene family consists of 4 members: fOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for FOSB.

Molecular Weight: 35kD

Gene ID: 2354

UniProt: P53539