FTH1 antibody (Internal Region)

Catalog No. ABIN7220828

The Rabbit Polyclonal anti-FTH1 antibody is suitable to detect FTH1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for FTH1 antibody (Internal Region) (ABIN7220828)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FTH1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Ferritin heavy chain Polyclonal Antibody

Specificity: Ferritin heavy chain Polyclonal Antibody detects endogenous levels of Ferritin heavy chain protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ferritin heavy chain

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain

Background: FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 proteinFTH1 encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Molecular Weight: 21kD

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis