FGF18 antibody (C-Term)

Catalog No. ABIN7217904

The Rabbit Polyclonal anti-FGF18 antibody is suitable to detect FGF18 in samples from Human, Mouse, Rat and Sheep. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for FGF18 antibody (C-Term) (ABIN7217904)

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Reactivity: Human, Mouse, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-FGF18 Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-FGF-18 Polyclonal Antibody

Specificity: FGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human FGF-18

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FGF18

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Alternative Name: FGF-18

Background: FGF18, Fibroblast growth factor 18, FGF-18, zFGF5Fibroblast growth factor 18 encoded by FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Molecular Weight: 28kD

Gene ID: 8817

UniProt: O76093

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway