FGF20 antibody (Internal Region)

Catalog No. ABIN7217898

The Rabbit Polyclonal anti-FGF20 antibody is suitable to detect FGF20 in samples from Mouse, Human and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for FGF20 antibody (Internal Region) (ABIN7217898)

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FGF20 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-FGF-20 Polyclonal Antibody

Specificity: FGF-20 Polyclonal Antibody detects endogenous levels of FGF-20 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human FGF-20

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FGF20

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Alternative Name: FGF-20

Background: FGF20, Fibroblast growth factor 20, FGF-20Fibroblast growth factor 20 encoded by FGF20 is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.

Molecular Weight: 23kD

Gene ID: 26281

UniProt: Q9NP95

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway