FLRT2 antibody (AA 170-250)

Catalog No. ABIN7228556

The Rabbit Polyclonal anti-FLRT2 antibody is suitable to detect FLRT2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for FLRT2 antibody (AA 170-250) (ABIN7228556)

Target: FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLRT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FLRT2 Antibody

Binding Specificity: AA 170-250

Purpose: Rabbit Anti-FLRT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FLRT2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FLRT2 protein at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FLRT2

Target: FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))

Alternative Name: FLRT2

Background: Leucine-rich repeat transmembrane protein FLRT2, Fibronectin-like domain-containing leucine-rich transmembrane protein 2FLRT2 encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants.

Molecular Weight: 72kD

Gene ID: 23768

UniProt: O43155