Fibulin 1 antibody

Catalog No. ABIN7228494

This Rabbit Polyclonal antibody specifically detects Fibulin 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Fibulin 1 antibody (ABIN7228494)

Target: Fibulin 1 (FBLN1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fibulin 1 Antibody

Purpose: Rabbit Anti-FBLN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FBLN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FBLN1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Fibulin 1

Target: Fibulin 1 (FBLN1)

Alternative Name: FBLN1

Background: Fibulin-1, FIBL-1Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. FBLN1 (Fibulin 1) is a Protein Coding gene. Diseases associated with FBLN1 include Synpolydactyly, 3/3'4, Associated With Metacarpal And Metatarsal Synostoses and Fbln1-Related Developmental Delay-Central Nervous System Anomaly-Syndactyly Syndrome. Among its related pathways are Elastic fibre formation and Cell adhesion_Cell-matrix glycoconjugates.

Molecular Weight: 77kD

Gene ID: 2192

UniProt: P23142