FIL1L antibody (AA 30-110)

Catalog No. ABIN7214602

The Rabbit Polyclonal anti-FIL1L antibody is suitable to detect FIL1L in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for FIL1L antibody (AA 30-110) (ABIN7214602)

Target: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIL1L antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-FIL1L Antibody

Binding Specificity: AA 30-110

Purpose: DOC-1 Polyclonal Antibody

Specificity: DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DOC-1 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FIL1L

Target: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Alternative Name: DOC-1

Background: Rabbit Anti-DOC-1 Polyclonal Antibody,CDK2AP1, CDKAP1, DOC1, Cyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor,Cyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,Cyclin-dependent kinase 2-associated protein 1

Molecular Weight: observerd band 20kDa

Gene ID: 8099

UniProt: O14519