FOLR1 antibody (AA 10-90)

Catalog No. ABIN7220726

This Rabbit Polyclonal antibody specifically detects FOLR1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FOLR1 antibody (AA 10-90) (ABIN7220726)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOLR1 Antibody

Binding Specificity: AA 10-90

Purpose: FR-α Polyclonal Antibody

Specificity: FR-α Polyclonal Antibody detects endogenous levels of FR-α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human FR-alpha at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FR-alpha

Background: Rabbit Anti-FR-α Polyclonal Antibody,FOLR1, FOLR, Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18,The folate receptor 1 encoded by FOLR1 is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.,Folate receptor alpha

Molecular Weight: observerd band 34kDa

Gene ID: 2348

UniProt: P15328

Pathways: Dicarboxylic Acid Transport