FOLR3 antibody

Catalog No. ABIN7228572

The Rabbit Polyclonal anti-FOLR3 antibody (ABIN7228572) specifically detects FOLR3 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for FOLR3 antibody (ABIN7228572)

Target: FOLR3 (Folate Receptor 3 (Gamma) (FOLR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOLR3 Antibody

Purpose: Rabbit Anti-FOLR3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FOLR3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FOLR3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FOLR3

Target: FOLR3 (Folate Receptor 3 (Gamma) (FOLR3))

Alternative Name: FOLR3

Background: Folate receptor gamma, FR-gamma, Folate receptor 3FOLR3 encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of FOLR3 may be elevated in ovarian and primary peritoneal carcinoma. FOLR3 is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. FOLR3 (Folate Receptor 3) is a Protein Coding gene. Diseases associated with FOLR3 include Primary Peritoneal Carcinoma. Among its related pathways are Innate Immune System and Antifolate resistance.

Molecular Weight: 26kD

Gene ID: 2352

UniProt: P41439

Pathways: Dicarboxylic Acid Transport