FOXC2 antibody

Catalog No. ABIN7228574

The Rabbit Polyclonal anti-FOXC2 antibody is suitable to detect FOXC2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for FOXC2 antibody (ABIN7228574)

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXC2 Antibody

Purpose: Rabbit Anti-FOXC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FOXC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FOXC2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FOXC2

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Alternative Name: FOXC2

Background: Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the development of mesenchymal tissues. FOXC2 (Forkhead Box C2) is a Protein Coding gene. Diseases associated with FOXC2 include Lymphedema-Distichiasis Syndrome and Distichiasis. Among its related pathways are Mesodermal Commitment Pathway and Adipogenesis. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription regulatory region DNA binding. An important paralog of this gene is FO.

Molecular Weight: 55kD

Gene ID: 2303

UniProt: Q99958