FOXO4 antibody (acLys189)

Catalog No. ABIN7228584

The Rabbit Polyclonal anti-FOXO4 antibody has been validated for WB and ELISA. It is suitable to detect FOXO4 in samples from Human.

Quick Overview for FOXO4 antibody (acLys189) (ABIN7228584)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXO4 Antibody

Binding Specificity: acLys189

Purpose: FoxO4 (Acetyl Lys189) Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FoxO4 when Acetyl occurs at Lys189

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FoxO4 (Acetyl Lys189) protein at AA range: 189

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Alternative Name: FoxO4

Background: Rabbit Anti-FoxO4 (Acetyl Lys189) Polyclonal Antibody,Forkhead box protein O4, Fork head domain transcription factor AFX1,FOXO4 encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving FOXO4 on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for FOXO4. FOXO4 (Forkhead Box O4) is a Protein Coding gene. Diseases associated with FOXO4 include Balloon Cell Malignant Melanoma and Sarcomatoid Squamous Cell Skin Carcinoma. Among its related pathways are AGE/RAGE pathway and RET signaling.,FoxO4

Molecular Weight: observerd band 55kDa

Gene ID: 4303

UniProt: P98177

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation