FOXO4 antibody (AA 206-240)

Catalog No. ABIN6242149

The Rabbit Polyclonal anti-FOXO4 antibody (Clone RB51229) (ABIN6242149) specifically detects FOXO4 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for FOXO4 antibody (AA 206-240) (ABIN6242149)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB51229

Product Details anti-FOXO4 Antibody

Binding Specificity: AA 206-240

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOXO4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from the Central region of human FOXO4.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Alternative Name: FOXO4

Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Molecular Weight: 53684

UniProt: P98177

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation