FRAT1 antibody (AA 130-210)

Catalog No. ABIN7228590

The Rabbit Polyclonal anti-FRAT1 antibody is suitable to detect FRAT1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for FRAT1 antibody (AA 130-210) (ABIN7228590)

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRAT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FRAT1 Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-FRAT1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FRAT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FRAT1 protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FRAT1

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Alternative Name: FRAT1

Background: Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1FRAT1 (FRAT1, WNT Signaling Pathway Regulator) is a Protein Coding gene. Among its related pathways are Endometrial cancer and Signaling by Wnt. An important paralog of this gene is FRAT2. The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.

Molecular Weight: 30kD

Gene ID: 10023

UniProt: Q92837