Fukutin antibody (AA 111-160)

Catalog No. ABIN7228550

This Rabbit Polyclonal antibody specifically detects Fukutin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Fukutin antibody (AA 111-160) (ABIN7228550)

Target: Fukutin (FKTN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fukutin Antibody

Binding Specificity: AA 111-160

Purpose: Rabbit Anti-FKTN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FKTN protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FKTN protein at AA range: 111-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN

Background: Fukutin, Fukuyama-type congenital muscular dystrophy proteinThe protein encoded by FKTN is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in FKTN are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for FKTN.

Molecular Weight: 50kD

Gene ID: 2218

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process