GPR161 antibody (AA 180-260)

Catalog No. ABIN7228714

The Rabbit Polyclonal anti-GPR161 antibody is suitable to detect GPR161 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for GPR161 antibody (AA 180-260) (ABIN7228714)

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR161 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GPR161 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-GP161 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GP161 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GP161 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GPR161

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Alternative Name: GP161

Background: G-protein coupled receptor 161, G-protein coupled receptor RE2The protein encoded by GPR161 is an orphan G protein-coupled receptor whose ligand is unknown. GPR161 is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, GPR161 is a potential drug target for triple-negative breast cancer.

Molecular Weight: 58kD

Gene ID: 23432

UniProt: Q8N6U8

Pathways: cAMP Metabolic Process