GPR3 antibody (AA 260-340)

Catalog No. ABIN7228734

The Rabbit Polyclonal anti-GPR3 antibody (ABIN7228734) specifically detects GPR3 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GPR3 antibody (AA 260-340) (ABIN7228734)

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-GPR3 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-GPR3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GPR3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GPR3 protein at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GPR3

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Alternative Name: GPR3

Background: G-protein coupled receptor 3, ACCA orphan receptorGPR3 is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.

Molecular Weight: 36kD

Gene ID: 2827

UniProt: P46089

Pathways: cAMP Metabolic Process