The Rabbit Polyclonal anti-GPR81 antibody (ABIN7228864) specifically detects GPR81 in WB and ELISA.
The antibody is reactive with Human and Mouse samples.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
Preservative
ProClin
Precaution of Use
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
GPR81
(G Protein-Coupled Receptor 81 (GPR81))
Alternative Name
HCAR1
Background
Hydroxycarboxylic acid receptor 1, G-protein coupled receptor 104, G-protein coupled receptor 81HCAR1 (Hydroxycarboxylic Acid Receptor 1) is a Protein Coding gene. Diseases associated with HCAR1 include Retinal Degeneration, Late-Onset, Autosomal Dominant. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR2. Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.