GTSE1 antibody (AA 70-150)

Catalog No. ABIN7228820

The Rabbit Polyclonal anti-GTSE1 antibody (ABIN7228820) specifically detects GTSE1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GTSE1 antibody (AA 70-150) (ABIN7228820)

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTSE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTSE1 Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-GTSE1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GTSE1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GTSE1 protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GTSE1

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Alternative Name: GTSE1

Background: G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homologThe protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. GTSE1 (G2 And S-Phase Expressed 1) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and CDK-mediated phosphorylation and removal of Cdc6.

Molecular Weight: 79kD

Gene ID: 51512

UniProt: Q9NYZ3