GABRD antibody (AA 110-190)

Catalog No. ABIN7220892

This Rabbit Polyclonal antibody specifically detects GABRD in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GABRD antibody (AA 110-190) (ABIN7220892)

Target: GABRD (GABA A Receptor delta (GABRD))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GABRD Antibody

Binding Specificity: AA 110-190

Purpose: GABAA Rδ Polyclonal Antibody

Specificity: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GABAA range: Rdelta at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Alternative Name: GABAA Rdelta

Background: Rabbit Anti-GABAA Rδ Polyclonal Antibody,GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta,Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. GABRD encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.,Gamma-aminobutyric acid receptor subunit delta

Molecular Weight: observerd band 51kDa

Gene ID: 2563

UniProt: O14764