Galanin Receptor 1 antibody (AA 140-220)

Catalog No. ABIN7220916

This Rabbit Polyclonal antibody specifically detects Galanin Receptor 1 in ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Galanin Receptor 1 antibody (AA 140-220) (ABIN7220916)

Target: Galanin Receptor 1 (GALR1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galanin Receptor 1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-Galanin Receptor 1 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-GALR1 Polyclonal Antibody

Specificity: GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GALR1 at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Galanin Receptor 1

Target: Galanin Receptor 1 (GALR1)

Alternative Name: GALR1

Background: GALR1, GALNR, GALNR1, Galanin receptor type 1, GAL1-R, GALR-1The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.

Gene ID: 2587

UniProt: P47211

Pathways: cAMP Metabolic Process