GABRE antibody (Internal Region)

Catalog No. ABIN7217688

The Rabbit Polyclonal anti-GABRE antibody is suitable to detect GABRE in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for GABRE antibody (Internal Region) (ABIN7217688)

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRE Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-GABAA Rε Polyclonal Antibody

Specificity: GABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GABAA range: Repsilon

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GABRE

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Alternative Name: GABAA Repsilon

Background: GABRE, Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilonThe product of GABRE belongs to the ligand-gated ionic channel (TC 1. A. ) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.

Molecular Weight: 57kD

Gene ID: 2564

UniProt: P78334

Pathways: Synaptic Membrane