GJA4 antibody (AA 50-130)

Catalog No. ABIN7221082

The Rabbit Polyclonal anti-GJA4 antibody (ABIN7221082) specifically detects GJA4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GJA4 antibody (AA 50-130) (ABIN7221082)

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GJA4 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-Connexin 37 Polyclonal Antibody

Specificity: Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Connexin 37 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Alternative Name: Connexin 37

Background: GJA4, Gap junction alpha-4 protein, Connexin-37, Cx37GJA4 encodes a member of the connexin gene family. The gap junction protein alpha 4 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Molecular Weight: 37kD

Gene ID: 2701

UniProt: P35212

Pathways: Cell-Cell Junction Organization