Cx40/GJA5 antibody (N-Term)

Catalog No. ABIN7218286

This Rabbit Polyclonal antibody specifically detects Cx40/GJA5 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Cx40/GJA5 antibody (N-Term) (ABIN7218286)

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cx40/GJA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cx40/GJA5 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-Connexin-40 Polyclonal Antibody

Specificity: Connexin-40 Polyclonal Antibody detects endogenous levels of Connexin-40 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Connexin-40

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Alternative Name: Connexin-40

Background: GJA5, Gap junction alpha-5 protein, Connexin-40, Cx40GJA5 is a member of the connexin gene family. The gap junction protein alpha 5 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Molecular Weight: 39kD

Gene ID: 2702

UniProt: P36382

Pathways: Cell-Cell Junction Organization