GJC1 antibody (C-Term)

Catalog No. ABIN7218874

The Rabbit Polyclonal anti-GJC1 antibody is suitable to detect GJC1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for GJC1 antibody (C-Term) (ABIN7218874)

Target: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GJC1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-Connexin-45 Polyclonal Antibody

Specificity: Connexin-45 Polyclonal Antibody detects endogenous levels of Connexin-45 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Connexin-45

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GJC1

Target: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Alternative Name: Connexin-45

Background: GJC1, GJA7, Gap junction gamma-1 protein, Connexin-45, Cx45, Gap junction alpha-7 proteinGJC1 is a member of the connexin gene family. The gap junction protein gamma 2 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.

Molecular Weight: 45kD

Gene ID: 10052

UniProt: P36383

Pathways: Cell-Cell Junction Organization