GJC2 antibody (AA 40-120)
Quick Overview for GJC2 antibody (AA 40-120) (ABIN7223712)
Target
See all GJC2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-120
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Purpose
- Connexin 47 Polyclonal Antibody
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Specificity
- Connexin 47 Polyclonal Antibody detects endogenous levels of Connexin 47 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the N-terminal region of human Connexin 47 at AA range: 40-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))
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Alternative Name
- Connexin 47
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Background
- Rabbit Anti-Connexin 47 Polyclonal Antibody,GJC2, GJA12, Gap junction gamma-2 protein, Connexin-46.6, Cx46.6, Connexin-47, Cx47, Gap junction alpha-12 protein,GJC2 (gap junction protein gamma 2) encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. GJC2 plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in GJC2 are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.,Gap junction gamma-2 protein
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Molecular Weight
- observerd band 47kDa
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Gene ID
- 57165
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UniProt
- Q5T442
Target
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