GJC2 antibody (AA 40-120)

Catalog No. ABIN7223712

The Rabbit Polyclonal anti-GJC2 antibody (ABIN7223712) specifically detects GJC2 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GJC2 antibody (AA 40-120) (ABIN7223712)

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GJC2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Connexin 47 Polyclonal Antibody

Specificity: Connexin 47 Polyclonal Antibody detects endogenous levels of Connexin 47 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Connexin 47 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GJC2

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Alternative Name: Connexin 47

Background: GJC2, GJA12, Gap junction gamma-2 protein, Connexin-46.6, Cx46.6, Connexin-47, Cx47, Gap junction alpha-12 proteinGJC2 (gap junction protein gamma 2) encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. GJC2 plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in GJC2 are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

Molecular Weight: 47kD

Gene ID: 57165

UniProt: Q5T442