Gastrokine 2 antibody (AA 30-110)

Catalog No. ABIN7228660

The Rabbit Polyclonal anti-Gastrokine 2 antibody is suitable to detect Gastrokine 2 in samples from Rat, Mouse and Human. It has been validated for WB and ELISA.

Quick Overview for Gastrokine 2 antibody (AA 30-110) (ABIN7228660)

Target: Gastrokine 2 (GKN2)

Reactivity: Rat, Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gastrokine 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Gastrokine 2 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-GKN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GKN2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GKN2 protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Gastrokine 2

Target: Gastrokine 2 (GKN2)

Alternative Name: GKN2

Background: Gastrokine-2, Blottin, Down-regulated in gastric cancer, Trefoil factor interactions(z) 1The secretory protein encoded by GKN2 (Gastrokine 2) is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. GKN2 may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. GKN2 is a Protein Coding gene. Diseases associated with GKN2 include Gastric Cancer, Somatic and Internuclear Ophthalmoplegia.

Molecular Weight: 20kD

Gene ID: 200504

UniProt: Q86XP6