GATA-2/3 antibody

Catalog No. ABIN7220986

The Rabbit Polyclonal anti-GATA-2/3 antibody is suitable to detect GATA-2/3 in samples from Human and Mouse. It has been validated for ELISA, WB, IF and IHC.

Quick Overview for GATA-2/3 antibody (ABIN7220986)

Target: GATA-2/3

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA-2/3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-GATA-2/3 Antibody

Purpose: Rabbit Anti-GATA-2/3 Polyclonal Antibody

Specificity: GATA-2/3 Polyclonal Antibody detects endogenous levels of GATA-2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GATA-3 around the non-phosphorylation site of S308

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GATA-2/3

Target: GATA-2/3

Background: GATA3, Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA2, Endothelial transcription factor GATA-2, GATA-binding protein 2GATA3 encodes GATA binding protein 3 which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

Gene ID: 2625

UniProt: P23771, P23769