Metabotropic Glutamate Receptor 3 antibody (AA 40-120)

Catalog No. ABIN7228796

This Rabbit Polyclonal antibody specifically detects Metabotropic Glutamate Receptor 3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Metabotropic Glutamate Receptor 3 antibody (AA 40-120) (ABIN7228796)

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Metabotropic Glutamate Receptor 3 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-GRM3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GRM3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GRM3 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Metabotropic Glutamate Receptor 3

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Alternative Name: GRM3

Background: Metabotropic glutamate receptor 3, mGluR3G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Molecular Weight: 96kD

Gene ID: 2913

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane