CD236/GYPC antibody (AA 11-60)

Catalog No. ABIN7227714

The Rabbit Polyclonal anti-CD236/GYPC antibody (ABIN7227714) specifically detects CD236/GYPC in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CD236/GYPC antibody (AA 11-60) (ABIN7227714)

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD236/GYPC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CD236/GYPC Antibody

Binding Specificity: AA 11-60

Purpose: Rabbit Anti-CD236 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD236

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD236 protein at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD236/GYPC

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Alternative Name: CD236

Background: Glycophorin-C, Glycoconnectin, Glycophorin-D, GPD, Glycoprotein beta, PAS-2', Sialoglycoprotein D, CD antigen CD236Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Gene ID: 2995

UniProt: P04921