CD42a antibody

Catalog No. ABIN7228724

The Rabbit Polyclonal anti-CD42a antibody (ABIN7228724) specifically detects CD42a in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CD42a antibody (ABIN7228724)

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD42a antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD42a Antibody

Purpose: Rabbit Anti-GPIX Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GPIX protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GPIX protein at AA range: Internal

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Alternative Name: GPIX

Background: Platelet glycoprotein IX, GP-IX, GPIX, Glycoprotein 9, CD_antigen: CD42aGP9 encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.

Molecular Weight: 19kD

Gene ID: 2815

UniProt: P14770