GP6 antibody

Catalog No. ABIN7228766

This anti-GP6 antibody is a Rabbit Polyclonal antibody detecting GP6 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for GP6 antibody (ABIN7228766)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GP6 Antibody

Purpose: GPVI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GPVI protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GPVI protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: GPVI

Background: Rabbit Anti-GPVI Polyclonal Antibody,Platelet glycoprotein VI, GPVI, Glycoprotein 6,GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Glycoprotein VI Platelet is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,GPVI

Molecular Weight: observerd band 55kDa

Gene ID: 51206

UniProt: Q9HCN6