GP6 antibody

Catalog No. ABIN7228766

The Rabbit Polyclonal anti-GP6 antibody (ABIN7228766) specifically detects GP6 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GP6 antibody (ABIN7228766)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GP6 Antibody

Purpose: Rabbit Anti-GPVI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GPVI protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GPVI protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: GPVI

Background: Platelet glycoprotein VI, GPVI, Glycoprotein 6GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Glycoprotein VI Platelet is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 55kD

Gene ID: 51206

UniProt: Q9HCN6