GAS2 antibody

Catalog No. ABIN7228616

The Rabbit Polyclonal anti-GAS2 antibody (ABIN7228616) specifically detects GAS2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GAS2 antibody (ABIN7228616)

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GAS2 Antibody

Purpose: Rabbit Anti-GAS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GAS2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GAS2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GAS2

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Alternative Name: GAS2

Background: Growth arrest-specific protein 2, GAS-2The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. GAS2 (Growth Arrest Specific 2) is a Protein Coding gene. Diseases associated with GAS2 include Gnathodiaphyseal Dysplasia. Among its related pathways are p70S6K Signaling and Akt Signaling. An important paralog of this gene is GAS2L3.

Molecular Weight: 34kD

Gene ID: 2620

UniProt: O43903

Pathways: Caspase Cascade in Apoptosis