GDF1 antibody

Catalog No. ABIN7228636

The Rabbit Polyclonal anti-GDF1 antibody (ABIN7228636) specifically detects GDF1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GDF1 antibody (ABIN7228636)

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDF1 Antibody

Purpose: Rabbit Anti-GDF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GDF1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GDF1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GDF1

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Alternative Name: GDF1

Background: Embryonic growth/differentiation factor 1, GDF-1GDF1 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations.

Molecular Weight: 40kD

Gene ID: 2657

UniProt: P27539