GDF10 antibody

Catalog No. ABIN7227490

This Rabbit Polyclonal antibody specifically detects GDF10 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GDF10 antibody (ABIN7227490)

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDF10 Antibody

Purpose: Rabbit Anti-BMP3B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of BMP3B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human BMP3B protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GDF10

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Alternative Name: BMP3B

Background: Growth/differentiation factor 10, GDF-10, Bone morphogenetic protein 3B, BMP-3B, Bone-inducing protein, BIPGDF10 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of GDF10 is associated with oral cancer.

Molecular Weight: 52kD

Gene ID: 2662

UniProt: P55107