GDF7 antibody (Internal Region)

Catalog No. ABIN7218800

The Rabbit Polyclonal anti-GDF7 antibody is suitable to detect GDF7 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for GDF7 antibody (Internal Region) (ABIN7218800)

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GDF7 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-GDF-7 Polyclonal Antibody

Specificity: GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GDF-7

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GDF7

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Alternative Name: GDF-7

Background: GDF7, Growth/differentiation factor 7, GDF-7GDF7 encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signaling molecules that regulate diverse processes in growth, repair and embryonic development. The encoded preproprotein is proteolytically processed to generate the mature protein, which may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma.

Molecular Weight: 47kD

Gene ID: 151449

UniProt: Q7Z4P5

Pathways: Tube Formation