GDF9 antibody (Internal Region)

Catalog No. ABIN7215046

This Rabbit Polyclonal antibody specifically detects GDF9 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for GDF9 antibody (Internal Region) (ABIN7215046)

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GDF9 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-GDF-9 Polyclonal Antibody

Specificity: GDF-9 Polyclonal Antibody detects endogenous levels of GDF-9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GDF-9

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GDF9

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Alternative Name: GDF-9

Background: GDF9, Growth/differentiation factor 9, GDF-9GDF9 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 9 regulates ovarian function. Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins.

Molecular Weight: 57kD

Gene ID: 2661

UniProt: O60383