GRB14 antibody (AA 50-130)

Catalog No. ABIN7215152

The Rabbit Polyclonal anti-GRB14 antibody is suitable to detect GRB14 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IHC (p).

Quick Overview for GRB14 antibody (AA 50-130) (ABIN7215152)

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRB14 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GRB14 Antibody

Binding Specificity: AA 50-130

Purpose: GRB14 Polyclonal Antibody

Specificity: GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GRB14 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GRB14

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Alternative Name: GRB14

Background: Rabbit Anti-GRB14 Polyclonal Antibody,GRB14, Growth factor receptor-bound protein 14, GRB14 adapter protein,Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.,Growth factor receptor-bound protein 14

Molecular Weight: observerd band 61kDa

Gene ID: 2888

UniProt: Q14449