GNAO1 antibody

Catalog No. ABIN7228690

The Rabbit Polyclonal anti-GNAO1 antibody (ABIN7228690) specifically detects GNAO1 in WB and ELISA. The antibody is reactive with Mouse, Human and Rat samples.

Quick Overview for GNAO1 antibody (ABIN7228690)

Target: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GNAO1 Antibody

Purpose: GNAO Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GNAO protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GNAO protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GNAO1

Target: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Alternative Name: GNAO

Background: Rabbit Anti-GNAO Polyclonal Antibody,Guanine nucleotide-binding protein G(o) subunit alpha,The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. GNAO1 (G Protein Subunit Alpha O1) is a Protein Coding gene. Diseases associated with GNAO1 include Epileptic Encephalopathy, Early Infantile, 17 and Neurodevelopmental Disorder With Involuntary Movements. Among its related pathways are GABAergic synapse and Regulation of CFTR activity (norm and CF).,GNAO

Molecular Weight: observerd band 38kDa

Gene ID: 2775

UniProt: P09471

Pathways: G-protein mediated Events